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CRC1755: CASCAID
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CRC1755: CASCAID

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  • Research
    • Remission
      • #01 Long-term remission of autoimmune diseases by B cell directed CD19 CAR T cell therapy
      • #02 Resolution of inflammation by B cell directed CAR T cell therapy
      • #03 Understanding IVIg triggered checkpoints leading to remission of autoimmune inflammation
      • #04 Tissue-level determinants of macrophage polarisation and histological healing
      • #05 Checkpoints of T cell tissue egress promoting remission in inflammatory bowel disease
      • #06 Changes in lymph node stromal cells by B-cell depleting therapies in resolution of inflammation
    • Resistance
      • #07 Systemic neutrophil imbalances as indicator and mediator of treatment resistance
      • #08 Mechanisms of CD19+ B cell mediated tissue remodelling as checkpoints in autoimmune- fibrosing disorders such as systemic sclerosis
      • #09 Characterisation of molecular resistance mechanisms against biological therapies in inflammatory bowel diseases
      • #10 Mechanisms of how acetylated proteins contribute to rheumatoid arthritis progression and relapse
    • Relapse
      • #11 Unraveling the role of ACOD1 in gut microbiota-driven relapse mechanisms of rheumatoid arthritis
      • #12 Functional role of TNF- and TNFR-superfamily members in treatment-refractory inflammatory bowel diseases
      • #13 The role of T cell responses in the persistence of systemic inflammation and treatment failure in inflammatory bowel disease
      • #14 Impact of a natural microbiota on gut inflammation and therapy response in IBD
      • #15 Fibroblast signatures associated with relapse of arthritis
    • Central
      • Z01 Integrative tissue profiling, omics data analysis support, and FAIR data management
      • Z02 Central tasks of the Collaborative Research Centre 1755
      • WIKO – IMMUNOVERSE: Designing and evaluating a metaversal playground for science
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Janina R., a lupus patient, gave birth to a child four years after receiving CAR T-cell therapy. Source: private

Pregnancy after CAR T-cell therapy
Digital Health You Can Experience in Rheumatology – From VR to an AI Symptom Checker
Why Diseases Return

Central


Z01 Integrative tissue profiling, omics data analysis support, and FAIR data management


Z02 Central tasks of the Collaborative Research Centre 1755


WIKO – IMMUNOVERSE: Designing and evaluating a metaversal playground for science

Friedrich-Alexander-Universität
Erlangen-Nürnberg

Freyeslebenstraße 1
91058 Erlangen
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